Fig. 3.

Histological cross section of H-E stained 8 mm biopsy punch wound in rabbit ear with A Normal skin. B H&E stained sections of mismatch siRNA/KALA-treated 8 mm biopsy punch wound after 56 post injury. As compared with weave-like collagen structure, parallel and less developed collagen bundles observed (depicted as an arrow). C CTGF siRNA/KALA-treated wound showed well stained epidermis layer as denoted an arrow and high density of fibroblasts and collagen bundles as weave-like in dermis layer (Original magnification × 400)