Fig. 8.

Structure and properties of collagen/chitosan scaffolds. A Microstructure of freeze-dried collagen/chitosan scaffold. B Change of mechanical properties of collagen/chitosan scaffold caused by the variation of chitosan concentration (0–50 wt%). C Remaining of collagen/chitosan scaffold after incubation for 28 days in serum containing media. Data (n = 3) is plotted in mean ± standard deviation. Significance is indicated by *p < 0.05; **p < 0.01; ***p < 0.001. D, E Determination of sGAG deposition of collagen (collagen:chitosan at 100:0) versus collagen/chitosan (collagen:chitosan at 75:25) scaffolds, by Safranin O staining (D) and sGAG quantification (E). Data (n = 3) is plotted in mean ± standard deviation. Significance is indicated by *p < 0.05; **p < 0.01; ***p < 0.001.

(Parts of figure are adapted, with permission, from [137] A, B and [139] C, D, E)