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. 2018 Nov 22;8:17246. doi: 10.1038/s41598-018-35589-9

Figure 2.

Figure 2

Interaction network of regulated putative substrates (direct or indirect) of all analyzed kinases and phosphatases. Kinases and their phosphorylation events are depicted in red color and phosphatases and their dephosphorylation events are depicted in black color. Proteins that are regulated by the respective kinases and phosphatases in the opposite direction are indicated by light grey lines. Respective putative direct substrates are depicted in brown. All proteins in the above interaction network are referred to as nodes and their interactions as edges.