Table 1.
Cox regression analysis of clinicopathological factors in PC.
| Cohort 2 | Univariable analysis | Multivariable model 1 | ||
|---|---|---|---|---|
| (nTOT = 45, nPCD = 29) | Significant factors | |||
| Variable | HR (95% CI) | p Value | HR (95% CI) | p Value |
| RGS2 (Cat.) | 2.172 (1.008–4.679) | 0.048 | 1.221 (0.505–2.953) | 0.658 |
| M-stage (Cat.) | 4.223 (1.412–12.632) | 0.01 | 3.911 (1.243–12.308) | 0.020 |
| PSA (Log10) | 1.860 (0.990–3.493) | 0.054 | ||
| GS (Cat.) | 1.645 (0.279–1.323) | 0.210 | ||
| T-stage (Cat.) | 0.589 (0.139–2.495) | 0.472 | ||
| Age (Cont.) | 0.988 (0.938–1.041) | 0.643 | ||
| Multivariable model 2 | Multivariable model 3 | |||
| Biomarker | Current diagnostic factors | |||
| Variable | HR (95% CI) | p Value | HR (95% CI) | p Value |
| RGS2 (Cat.) | 2.08 (0.915–4.728) | 0.032 | ||
| M-stage (Cat.) | ||||
| PSA (Log10) | 1.555 (0.806–3.001) | 0.188 | 1.873 (0.987–3.552) | 0.055 |
| GS (Cat.) | 1.786 (0.810–3.938) | 0.151 | ||
| T-stage (Cat.) | 0.611 (0.141–2.648) | 0.51 | ||
| Age (Cont.) | ||||
Results from Cox regression analysis presented as hazard ratio (HR) with the 95% confidence interval (CI) and p-value. For RGS2 the median categories were used. GS was divided according GS6-7 vs. GS8-9, T-stage T1-T2 vs. T3-T4, M-stage M0 vs. M1. Age was used as a continuous variable and for PSA a log10 transformation was applied. Additional abbreviation: Prostate cancer death (PCD).