Table 1.
Top HSF1-regulated genes in healthy CGNs.
| Genes | Fold change | Protein description |
|---|---|---|
| Slc34a2* | 616.946 | Sodium-dependent phosphate transport protein 2B |
| Crybb1 | 308.205 | Beta-crystallin B1 |
| Krt42 | 195.526 | Keratin, type I cytoskeletal 42 |
| Crabp1 | 122.264 | Cellular retinoic acid-binding protein 1 |
| Apob* | 112.260 | Apolipoprotein B |
| Ovol2 | 95.548 | Ovo-like zinc finger 2, C2H2 zinc finger transcription factor of the Ovo-like family |
| Angptl1 | 94.663 | Angiopoietin-like 1, ligand for endothelial tyrosine-kinase receptor Tek |
| Nmb* | 88.659 | Neuromedin B, bombesin-related peptide |
| Plac9* | 88.374 | Placenta-specific 9 |
| Kank4 | 79.895 | KN motif and ankyrin-repeat domain-containing protein 4 |
| Myo1h | 79.506 | Myosin IH |
| Rfx6 | 76.643 | Regulatory factor X6, transcription factor of the RFX family |
| Pitx2 | 71.177 | Paired-like homeodomain transcription factor 2 |
| Sox15* | 66.873 | SRY box 15, transcription factor of the SOX family |
| Pax7* | 59.913 | Paired box 7, transcription factor of the paired box family |
| Igfbpl1* | 59.809 | Insulin-like growth factor binding protein-like 1 |
| Nodal | 55.864 | Nodal growth differentiation factor, morphogen, ligand of the TGFβ signaling pathway |
| Tchh | 54.351 | Trichohyalin |
| Mcoln2 | 51.025 | Mucolipin-2, cation channel protein |
| Gipc3 | 50.950 | GIPC PDZ domain-containing family member 3 |
Note: Uncharacterized genes are not listed. *Common genes between HK and LK.