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. 2018 Nov 22;8:17255. doi: 10.1038/s41598-018-35610-1

Table 2.

Top HSF1-regulated genes in apoptotic CGNs.

Genes Fold change Protein description
Rbm12 107.500 RNA-binding motif protein 12
Dmrt1 63.926 Doublesex and mab-3 related transcription factor 1
Acan 34.704 Aggrecan, extracellular matrix protein
Slc34a2* 33.350 Sodium-dependent phosphate transport protein 2B
Zfp93 26.539 Zinc finger protein 93
Alx4 26.088 ALX homeobox 4, paired-like homeodomain transcription factor
Pax7* 25.004 Paired box 7, transcription factor of the paired box family
Apob* 20.516 Apolipoprotein B
Fbxw10 16.614 F-box and WD repeat domain-containing 10, targeting proteins for ubiquitination
Nmb* 16.136 Neuromedin B, bombesin-related peptide
Igfbpl1* 15.883 Insulin-like growth factor binding protein-like 1
Plac9* 14.963 Placenta-specific 9
Batf 12.539 Basic leucine zipper ATF-like transcription factor
Crhr2 11.869 Corticotropin-releasing hormone receptor 2
Cryab 11.292 Crystallin alpha B, heat shock protein of the crystallin family
Sctr 10.478 Secretin receptor
Spetex-2F 10.413 Spetex-2F protein
Sox15* 10.363 SRY box 15, transcription factor of the SOX family
Ccdc180 10.078 Coiled-coil domain containing 180
Amz1 10.049 Archaelysin family metallopeptidase 1

Note: Uncharacterized genes are not listed. *Common genes between HK and LK.