Table 2. Summary of OR and 95% CI values for TIM-3 rs1036199 polymorphism and AD risk.
G vs T | GT vs TT | ||||
---|---|---|---|---|---|
Variables | N | OR (95%CI) | P/I2(%) | OR (95%CI) | P/I2(%) |
Total | 10 | 1.59 (1.17–2.17) | 0.030/51.3 | 1.68 (1.37–2.06) | 0.142/33.3 |
Ethnicity | |||||
Asian | 9 | 1.76 (1.43–2.18) | 0.257/21.0 | 1.82 (1.46–2.28) | 0.237/23.1 |
African | 1 | – | – | – | – |
Source of control | |||||
HB | 5 | 1.45 (1.07–1.97) | 0.577/0.0 | 1.41 (1.02–1.94) | 0.685/0.0 |
PB | 5 | 1.93 (1.08–3.45) | 0.004/74.2 | 2.10 (1.28–3.43) | 0.046/58.7 |
Disease type | |||||
RA | 4 | 1.88 (1.45–2.44) | 0.120/48.6 | 2.02 (1.53–2.65) | 0.123/48.1 |
Others | 6 | 1.23 (0.94–1.61) | 0.147/38.8 | 1.35 (1.00–1.83) | 0.511/0.0 |
Abbreviations: HB, hospital-based; N, number of studies; P, P value of Q-test for heterogeneity; PB, population-based.