Table 4.
Genes showing elevated expression in TAMRA+ Krebs-2 carcinoma cells relative to TAMRA− cells, and participating in formation and maintenance of stem properties of tumorigenic as well as normal pluri-/multipotent stem cells.
| Gene | Proof for the role in CSCs formation and maintenance | Proof for the role in normal pluri-/multi-potent stem cells formation and maintenance | |
|---|---|---|---|
| 1 | Abca1 | Sun et al., 2015 | Peeters et al., 2006 |
| 2 | Abca13 | N/C | Barbet et al., 2012 |
| 3 | Aldh1a1 | Yang et al., 2014c | Dey et al., 2015 |
| 4 | Aldh1l1 | Hartomo et al., 2015; Wang et al., 2016d | Foo and Dougherty, 2013 |
| 5 | Acpp | Liu et al., 2014 | N/C |
| 6 | Alox15 | Chen et al., 2014d | Kinder et al., 2010 |
| 7 | Arg2 | N/C | Chen et al., 2015b |
| 8 | Asb4 | N/C | Yang et al., 2014b |
| 9 | Cacna1d | Gerber et al., 2013 | N/C |
| 10 | Ccr3 | Long et al., 2012 | Krathwohl, 2004 |
| 11 | Cd55 | Saygin et al., 2017 | Ardianto et al., 2010 |
| 12 | Cd200 | Jung et al., 2015b | Wang et al., 2014 |
| 13 | Cldn1 | Mahati et al., 2017a | Zinner et al., 2013 |
| 14 | Clec11a | Hiraoka, 2008 | Hiraoka et al., 2001 |
| 15 | Col3a1 | Januchowski et al., 2016 | N/C |
| 16 | Cp | Tye et al., 2008; Brandi et al., 2016 | N/C |
| 17 | Crabp2 | Kim et al., 2010 | Steidl et al., 2005 |
| 18 | Cyp26a1 | N/C | Assou et al., 2007 |
| 19 | Ddx3y | Rosinski et al., 2008 | Kotov et al., 2017 |
| 20 | Fblim1 | N/C | Xiao et al., 2012 |
| 21 | Fgfr1 | Ji et al., 2016 | Coutu et al., 2011 |
| 22 | Gas6 | Jin et al., 2017b | Gely-Pernot et al., 2012 |
| 23 | Gata6 | Whissell et al., 2014 | Kubo et al., 2009 |
| 24 | Grb10 | N/C | Li et al., 2017a |
| 25 | Igf1 | Bu et al., 2014 | Li et al., 2010b |
| 26 | Igf2 | Tominaga et al., 2017 | Bendall et al., 2007 |
| 27 | Il10 | Tuccitto et al., 2016 | Liu et al., 2012; de Almeida et al., 2014; Lee et al., 2015b |
| 28 | Il17rb | Bie et al., 2016 | Bie et al., 2017 |
| 29 | Itln1 | N/C | Zhao et al., 2015 |
| 30 | Lhx4 | N/C | Chen et al., 2005 |
| 31 | Mmp2 | Sun et al., 2013; An et al., 2015 | Huang et al., 2011 |
| 32 | Nfatc2 | Perotti et al., 2016 | Kiani et al., 2004 |
| 33 | Nt5e | Katsuta et al., 2016 | Corradetti et al., 2013 |
| 34 | Nts | Zhou et al., 2014 | Cai et al., 2015 |
| 35 | Pdk4 | Song et al., 2015 | Takubo et al., 2013 |
| 36 | Per2 | N/C | Boucher et al., 2016 |
| 37 | Pf4 | N/C | Han et al., 1997; Calaminus et al., 2012; Chen et al., 2014b |
| 38 | Prok2 | N/C | LeCouter et al., 2004 |
| 39 | S100a14 | Leth-Larsen et al., 2012; Ko et al., 2013 | N/C |
| 40 | Tal1 | Gerby et al., 2016 | Baharvand et al., 2006; Souroullas et al., 2009 |
| 41 | Tcf7l2 | Chen et al., 2015a | Quan et al., 2016 |
| 42 | Thpo | Chou et al., 2012 | Kohlscheen et al., 2015 |
| 43 | Tnn | N/C | Tucker et al., 2013 |
| 44 | Vsig4 | Zhang et al., 2016c | N/C |
| 45 | Wnt5a | Zhou et al., 2017 | Hao et al., 2006 |