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. 2018 Nov 16;9:2776. doi: 10.3389/fmicb.2018.02776

FIGURE 7.

FIGURE 7

Perturbations of nucleotide metabolism. (A) Heatmap profiles of the relative abundance of nucleotide metabolites after treated with colistin (COL), aztreonam (AZT) and the combination (COL/AZT) at 1, 4, and 24 h. (B) Significantly altered metabolites associated with nucleotide metabolism due to aztreonam alone and the combination of colistin and aztreonam at 1, 4, and 24 h in A. baumannii AB090342. log2 FC ≥ 1 or ≤ –1, p < 0.05, FDR < 0.05 (one-way ANOVA). Metabolomics data were collected from five biological replicates per condition.