Table 1.
Demographics and baseline clinical characteristics for recipients n (%)
| Variable | PTMS (n = 20) | Non-PTMS (n = 127) | P value |
| Demographics | |||
| Age, yr | 46.3 ± 9.0 | 45.5 ± 11.0 | 0.746 |
| Male | 17 (85.0) | 104 (81.9) | 0.735 |
| BMI, kg/m2 | 23.5 ± 4.3 | 21.8 ± 2.8 | 0.021 |
| MELD score | 18.4 ± 8.3 | 17.7 ± 8.5 | 0.768 |
| Child-Pugh score | 10.5 ± 2.2 | 10.0 ± 2.0 | 0.374 |
| Smoking | 5 (25.0) | 39 (30.7) | 0.604 |
| Alcohol | 6 (30.0) | 19 (15.0) | 0.096 |
| HBV | 13 (65.0) | 85 (66.9) | 0.865 |
| HCV | 1 (5.0) | 14 (11.0) | 0.408 |
| Pre-LT comorbidity | |||
| Obesity | 4 (20.0) | 4 (3.1) | 0.002 |
| Diabetes mellitus | 4 (20.0) | 13 (10.2) | 0.210 |
| Hypertension | 1 (5.0) | 4 (3.1) | 0.671 |
| Dyslipidemia | 2 (10.0) | 13 (10.2) | 0.974 |
| Metabolic syndrome | 3 (10.0) | 4 (3.1) | 0.020 |
| Laboratory test | |||
| Pre-LT serum uric acid, μmol/L | 265 ± 116 | 280 ± 97 | 0.545 |
| Pre-LT serum creatinine, μmol/L | 55.2 ± 16.9 | 60.0 ± 19.0 | 0.288 |
| Pre-LT eGFR, mL/min per 1.73 m2 | 158.7 ± 54.6 | 139.2 ± 43.9 | 0.076 |
| Operative characteristic | |||
| Anhepatic phase, min | 50.8 ± 9.5 | 53.5 ± 11.3 | 0.193 |
| Operation time, h | 6.7 ± 1.5 | 6.2 ± 1.1 | 0.084 |
| Length of ICU stay, d | 6.9 ± 3.0 | 6.8 ± 3.6 | 0.923 |
| Post-LT clinical characteristic | |||
| Steroid-free protocol for HCC | 3 (15.0) | 43 (33.9) | 0.091 |
| Tacrolimus use ≥ 24 mo | 12 (60.0) | 68 (53.5) | 0.590 |
| Cyclosporine use ≥ 24 mo | 8 (40.0) | 59 (46.5) | 0.590 |
| MMF use ≥ 24 mo | 13 (65.0) | 84 (66.1) | 0.920 |
| Acute graft rejection | 3 (15.0) | 12 (9.4) | 0.446 |
| Biliary complication | 3 (15.0) | 28 (22.0) | 0.472 |
| Acute kidney injury | 7 (35.0) | 13 (10.2) | 0.002 |
| Hyperuricemia | 11 (55.0) | 19 (15.0) | 0.002 |
PTMS: Posttransplant metabolic syndrome; BMI: Body mass index; MELD: Model for end-stage liver disease; HBV: Hepatitis B virus; HCV: Hepatitis C virus; LT: Liver transplantation; eGFR: Estimated glomerular filtration rate; ICU: Intensive care unit; HCC: Hepatocellular carcinoma; MMF: Mycophenolate mofetil.