Fig. 2.

Kaplan–Meier curves representing survival time differences across the different cohorts with a cut-off of five tumour buds for low- or high-grade budding. a AMC-AJCCII-90, b LUMC, c CAIRO, and d CAIRO2. Differences in survival are reported as univariate hazard ratios with 95% confidence intervals, and p values were calculated using the log-rank method