Table 2.
Unadjusted univariate | Multivariatea RR (95%CI) | |||
---|---|---|---|---|
Category | Factor | RR (95% CI) | (N=1453) | P value |
Subject | Age (per 10 y) | 1.04 (0.95–1.15) | ||
Sex | ||||
Male | Reference | |||
Female | 0.98 (0.86–1.12) | |||
Race | ||||
White | reference | reference | .004 | |
Black | 1.35 (1.10–1.66) | 1.41 (1.14–1.75) | ||
Asian/Pacific Islander | 1.66 (1.20–2.30) | 1.72 (1.22–2.43) | ||
Other/multiple/unknown | 0.71 (0.51–0.98) | 0.73 (0.52–1.03) | ||
Hispanic (% yes) | ||||
No | reference | |||
Yes | 0.96 (0.74–1.23) | |||
Smoking status | ||||
Never | reference | |||
Former | 1.11 (0.97–1.26) | |||
Current | 1.20 (0.96–1.51) | |||
BMI | ||||
<25 | reference | |||
25–29.9 | 0.91 (0.77–1.08) | |||
≥ 30 | 1.08 (0.91–1.27) | |||
Family history of CRC | ||||
No | reference | reference | .01 | |
Yes | 1.23 (1.05–1.45) | 1.26 (1.07–1.48) | ||
Exam | Indication | |||
Screening | reference | |||
Follow-up exam | 1.21 (1.05–1.39) | |||
Diagnostic | 0.98 (0.81–1.20) | |||
Quality of preparationa | <.0001 | |||
Excellent | reference | reference | ||
Good | 1.58 (1.34–1.87) | 1.50 (1.26–1.78) | ||
Adequate | 1.70 (1.31–2.21) | 1.60 (1.23–2.10) | ||
Fair/poor | 2.14 (1.66–2.75) | 2.16 (1.66–2.83) | ||
Not stated in report | 2.15 (1.77–2.60) | 2.12 (1.74–2.60) | ||
Endoscopist | Age (per 10 years) | 0.90 (0.84–0.97) | ||
Gender | ||||
Male | reference | |||
Female | 0.87 (0.72–1.05) | |||
Specialty | .001 | |||
Gastroenterology | reference | reference | ||
Internal medicine/General surgery/Other | 1.41 (1.15–1.74) | 1.45 (1.16–1.79) | ||
Index findings | No. of adenomas | <.0001 | ||
1 | reference | reference | ||
2 | 1.50 (1.30–1.73) | 1.47 (1.27–1.71) | ||
No. of serrated polyp | .0003 | |||
0 | reference | reference | ||
1–2 | 1.33 (1.15–1.55) | 1.29 (1.10–1.50) | ||
3+ | 2.01 (1.50–2.69) | 2.16 (1.59–2.93) | ||
Clinically significant serrated polypb | ||||
No | reference | |||
Yes | 1.31 (1.05–1.63) |
BMI, body mass index; CI, confidence interval; CRC, colorectal cancer; RR, relative risk.
Multivariate model after removing variables stepwise with P < .05.
A clinically significant serrated polyp is defined as a sessile serrated adenoma, a traditional serrated adenoma, a proximal serrated polyp, or a serrated polyp ≥1 cm.