Table 4.
Achievement of Surviving Sepsis Campaign bundle targets in 59 ICUs, Japan (n = 1184)
| Compliance rate | |
|---|---|
| Compliance with all applicable elements of sepsis 3-h bundle | |
| Entire 3-h resuscitation bundlea | 543/844 (64.3) |
| B1. Serum lactate obtained | 1143/1180 (96.9) |
| B2. Broad-spectrum antibiotic given | 985/1179 (83.5) |
| B3. Blood cultures obtained before broad-spectrum antibiotic administration | 1084/1178 (92.0) |
| B4. 30 mg/kg crystalloid fluid bolus delivered (yes/cases with indication)a | 645/845 (76.3) |
| Compliance with all applicable elements of sepsis 6-h bundle | |
| Entire 6-h resuscitation bundleb | 41/688 (3.5) |
| Vasopressors use + re-measured lactate | 625/752 (83.1) |
| B5. Vasopressor use followed initial fluid bolus if needed to maintain MAP ≥ 65 mmHg (yes/cases with indication) | 745/841 (88.6) |
| B6. CVP measured (yes/cases with indication)a | 225/856 (26.3) |
| B7. CVP 8 mmHg achieved (yes/cases with indication)a | 181/227 (79.7) |
| B8. ScvO2 measured (yes/cases with indication)a | 60/853 (7.0) |
| B9. ScvO2 70% (or SvO2 65%) achieved (yes/cases with indication)a | 49/66 (74.2) |
| B10. Re-measured lactate if initial lactate elevated (yes/cases with indication) | 864/960 (90.0) |
| Entire 3-h resuscitation bundle + vasopressors use + re-measured lactate | 397/693 (57.3) |
| Entire 3-h resuscitation bundle + vasopressors use | 449/750 (59.9) |
Reported counts (proportions). Missing data: B1 = 4, B2 = 5, B3 = 6, B4 = 9, B5 = 7, B6 = 10, B7 = 757, B8 = 9, B9 = 899, B10 = 14
MAP mean arterial pressure, CVP central venous pressure, ScvO2 central venous oxygen saturation, SvO2 mixed venous oxygen saturation, ICU intensive care unit
aSeptic shock or lactate > 4 mmol/L
bExcluded the achievement of a CVP of 8 mmHg and a ScvO2 of 70% from the entire 6-h bundle analysis