Table 7.
Relationship between epidemiological and treatment factors and in-hospital mortality among patients with severe sepsis using a generalized estimating equation model (n = 952)
| Characteristics | Odds_(95%CI) |
|---|---|
| Age at admission, years | 1.02_(1.01–1.04) |
| Male sex | 0.81_(0.57–1.14) |
| Body mass index | 1_(0.97–1.04) |
| ADL | 0.88_(0.58–1.32) |
| Admission source | |
| ED | reference |
| w/o ED (transfer or other department) | 1.12_(0.78–1.62) |
| ICU | 1.99_(0.91–4.36) |
| CCI | 1.2_(1.09–1.32) |
| Septic shock | |
| Yes | 1.01_(0.63–1.62) |
| Suspected site of infection | |
| Lung | reference |
| Abdomen | 0.54_(0.35–0.85) |
| Urinary tract | 0.22_(0.12–0.41) |
| Soft tissue | 0.73_(0.4–1.33) |
| Others | 1.16_(0.7–1.89) |
| SOFA score | 1.18_(1.12–1.24) |
| Positivity of blood cultures (bacteremia) | 1.16_(0.82–1.64) |
| Fluid resuscitation protocola | |
| Not achievement | reference |
| Achievement | 1.14_(0.72–1.82) |
| Not indicated | 1.06_(0.59–1.91) |
| Broad-spectrum antibiotic use | 1.04_(0.66–1.64) |
Missing data: body mass index = 26, admission source = 2, ADL = 2, positivity of blood cultures = 7, Sepsis-related Organ Failure Assessment (SOFA) = 183, fluid resuscitation protocol = 9, broad-spectrum antibiotic use = 5
ED emergency department, ICU intensive care unit, CCI Charlson Comorbidity Index, ADL activities of daily living
aCrystalloid fluid bolus (30 mg/kg) delivered if it was indicated in the bundle in Surviving Sepsis Campaign Guidelines 2012