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Dependence of absolute CBF underestimation with semi-infinite model (i.e., actual CBF divided by the computed CBF with the semi-infinite model) on (a) extracerebral layer thickness, (b) source–detector separation for TR-NIRS measurement, (c) CBF, (d) cerebral to extra-CBF, (e) and (f) extracerebral and cerebral total hemoglobin concentration, and (g) and (h) extracerebral and cerebral tissue reduced scattering coefficients.
