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. 2018 Nov 20;12(2):320–335. doi: 10.1016/j.tranon.2018.10.002

Figure 1.

Figure 1

(A) Percent animal survival Kaplan-Meier curve for UT and TMZ-, OKN-007–, and combined OKN-007 and TMZ–treated G55 glioma-bearing mice. All treatment groups were found to have a significantly higher survival (P < .05 or more) compared to UT G55-glioma-bearing mice. The combined treatment group was found to have a significantly higher percent survival (P < .01) than the TMZ-treated group. (B) In vivo tumor volumes (mm3) obtained at days 19-22 following MRI detection of tumors (>5 mm3). All treatment groups were found to have significantly lower tumor volumes (P < .01 or more) compared to the UT group. N = 5 for each treatment group.