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. 2018 Nov 20;13:3777–3790. doi: 10.2147/COPD.S182504

Figure 2.

Figure 2

Circulating miR-190a-5p levels have diagnostic and prognostic value in COPD-PH patients.

Notes: (A) ROC curve showing that the levels of miR-190a-5p have a significant value in the prediction of patients with PH. (B) ROC curve showing that the levels of miR-190a-5p in patients with COPD-PH have a better predictive value than that in patients with PH. (C) Kaplan–Meier survival curves indicate there is no relationship between the miR-190a-5p levels and all-cause death in patients with PH. The cutoff point (2.0) is derived from the ROC curve. (D) Kaplan–Meier survival curves indicate that patients with lower levels of miR-190a-5p have better event-free survival in the COPD-PH subgroup. The cutoff point (2.75) is derived from the ROC curve.

Abbreviations: COPD-PH, pulmonary hypertension secondary to chronic obstructive pulmonary disease; PH, pulmonary hypertension; ROC, receiver operator characteristic.