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Evaluation of the cytotoxicity effect of exosome-based LNA-anti-miR- 142-3p delivery on 4T1 and TUBO cells.
Notes: After 48 hours of co-culture, unloaded exosomes and LNA-anti-miR negative control loaded exosomes showed nonsignificant toxicity vs untreated cells, while LNA-anti-miR-142-3p loaded exosomes showed significant cytotoxicity in both 4T1 and TUBO cell lines (*P<0.05). The results are representative of three independent experiments.
Abbreviation: LNA, locked nucleic acid.
