TABLE 3.
Adjusted mean metabolite pattern scores according to dietary pattern score among Asian Indians, aged 45–79 y, in the MASALA pilot study1
| All participants (n = 145)2 | Participants without type 2 diabetes (n = 105)3 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Western/Nonvegetarian dietary pattern | Vegetarian dietary pattern | Nonvegetarian dietary pattern | Vegetarian dietary pattern | |||||||||
| Low scores (<0) | High scores (>0) | P | Low scores (<0) | High scores (>0) | P | Low scores (<0) | High scores (>0) | P | Low scores (<0) | High scores (>0) | P | |
| Metabolite pattern 14 | ||||||||||||
| Model 1 | 0.118 ± 0.100 | −0.180 ± 0.123 | 0.06 | 0.049 ± 0.101 | −0.074 ± 0.122 | 0.44 | 0.138 ± 0.117 | −0.091 ± 0.134 | 0.20 | 0.136 ± 0.114 | −0.108 ± 0.140 | 0.18 |
| Model 2 | 0.232 ± 0.192 | −0.100 ± 0.208 | 0.07 | 0.148 ± 0.197 | 0.028 ± 0.217 | 0.56 | 0.267 ± 0.207 | 0.081 ± 0.218 | 0.35 | 0.276 ± 0.207 | 0.040 ± 0.235 | 0.31 |
| Model 3 | 0.236 ± 0.195 | −0.098 ± 0.211 | 0.07 | 0.149 ± 0.199 | 0.023 ± 0.222 | 0.55 | 0.266 ± 0.209 | 0.079 ± 0.222 | 0.35 | 0.276 ± 0.210 | 0.039 ± 0.234 | 0.31 |
| Metabolite pattern 25 | ||||||||||||
| Model 1 | −0.152 ± 0.093 | 0.220 ± 0.115 | 0.01 | 0.010 ± 0.095 | −0.022 ± 0.115 | 0.83 | −0.066 ± 0.106 | 0.280 ± 0.122 | 0.03 | 0.126 ± 0.105 | 0.020 ± 0.130 | 0.53 |
| Model 2 | −0.374 ± 0.170 | 0.030 ± 0.185 | 0.01 | −0.174 ± 0.177 | −0.270 ± 0.194 | 0.60 | −0.157 ± 0.182 | 0.205 ± 0.193 | 0.04 | 0.089 ± 0.186 | −0.141 ± 0.211 | 0.27 |
| Model 3 | −0.350 ± 0.169 | 0.042 ± 0.182 | 0.02 | −0.168 ± 0.175 | −0.224 ± 0.194 | 0.76 | −0.160 ± 0.185 | 0.202 ± 0.196 | 0.04 | 0.084 ± 0.189 | −0.148 ± 0.214 | 0.27 |
1Values are adjusted mean ± SE metabolite pattern scores calculated by using linear regression. Model 1 adjusted for age (years) and sex; model 2 adjusted as for model 1 plus for smoking (never, past smoker, or current smoker), education (high school or less, less than Bachelor's degree, Bachelor's degree, or more than Bachelor's degree), BMI (kg/m2), physical activity (metabolic equivalent task hours per week), and total energy intake (kilocalories per day); model 3 adjusted as for model 2 plus for prevalent hypertension (yes or no). AAA, aromatic amino acid; AC, acylcarnitine; MASALA, Metabolic Syndrome and Atherosclerosis in South Asians Living in America.
2Among all participants, model 3 was additionally adjusted for prevalent diabetes status (yes or no).
3Among participants without type 2 diabetes, a vegetarian pattern was identified in the first principal component, whereas a nonvegetarian pattern was identified in the second principal component.
4Medium- to long-chain ACs.
5BCAA, AAA, and short-chain AC pattern.