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. 2017 May 16;76(5):358–375. doi: 10.1093/jnen/nlx017

TABLE 1.

Cell Types of the VZ in Human Fetuses

Cell Type Function Basal Process Cilia Immuno-histochemical Markers Predominant Ventricle Wall Locationa Figures
1 Uncommitted NSCb Long radial One GFAP+, AQP 4+, βIV-tub- Lateral and dorsal 2, 7, Sup 2–5
2 Early pre-ependymal NSC Long radial One GFAP+, βIV-tub+ Lateral and dorsal 7, Sup 2, 3
3 Late pre-ependymal NSC Long radial One GFAP-, βIV-tub+ Lateral and dorsal 2, 7, Sup 3
4 Committed early ependyma Short None GFAP+, βIV-tub+ Lateral and medial 6, 7, Sup 2
5 Immature ependyma Short Multi GFAP+, βIV-tub+ Medial 6, Sup 2–5
6 Immature ependyma Short Multi GFAP−, βIV-tub+ Medial 6, 7, Sup 4
7 Mature ependyma None Multi GFAP−, βIV-tub+ Medial 7, Sup 5
a

During the second half of gestation.

b

NSC, also regarded as radial glia.

GFAP+, glial fibrillary acidic protein-positive; βIV-tub+, βIV-tubulin-positive. βIV-tubulin is a component of the cilium microtubules. Sup, Supplementary Data figures.