TABLE 1.
Quartile of fructose:vitamin C intake ratio | |||||
---|---|---|---|---|---|
Overall study population | Quartile 1: 0.0–0.1 | Quartile 2: 0.1–0.2 | Quartile 3: 0.2–0.3 | Quartile 4: 0.3–4.6 | |
(n = 4576) | (n = 1144) | (n = 1144) | (n = 1144) | (n = 1144) | |
Age, y | 55.5 ± 12.6 | 58.3 ± 12.0 | 55.3 ± 12.7 | 54.3 ± 13.0 | 54.2 ± 12.5 |
Male sex, % | 35.4 | 31.8 | 35.7 | 38.5 | 35.7 |
BMI, kg/m2 | 31.8 ± 7.2 | 31.6 ± 7.1 | 31.8 ± 6.8 | 31.6 ± 7.3 | 32.1 ± 7.7 |
Waist circumference, cm | 100.6 ± 16.1 | 100.6 ± 16.3 | 100.5 ± 15.3 | 100.2 ± 16.6 | 101.0 ± 16.0 |
Systolic blood pressure, mm Hg | 126.9 ± 18.2 | 127.1 ± 17.6 | 126.0 ± 17.5 | 127.5 ± 18.9 | 127.1 ± 18.9 |
eGFR, mL/(min × 1.73 m2) | 94.0 ± 21.7 | 91.8 ± 21.3 | 93.9 ± 21.6 | 94.9 ± 22.4 | 95.6 ± 21.2 |
Smoking status, % | |||||
Current smoker | 12.3 | 10.1 | 10.5 | 11.5 | 17.1 |
Former smoker | 18.7 | 21.7 | 17.0 | 16.3 | 19.8 |
Never smoker | 69.0 | 68.3 | 72.6 | 72.2 | 63.1 |
Hypertension (yes), % | 60.1 | 64.5 | 60.8 | 58.7 | 56.6 |
Diabetes (yes), % | 21.7 | 28.5 | 25.1 | 18.0 | 15.2 |
Diuretic medication use, % | 32.6 | 38.4 | 33.7 | 28.8 | 29.7 |
Vitamin C supplement use, % | 9.0 | 30.2 | 3.0 | 1.9 | 1.0 |
Fructose:vitamin C intake ratio, g/mg | 0.20 (0.13–0.30) | 0.08 (0.04–0.11) | 0.16 (0.14–0.18) | 0.24 (0.22–0.27) | 0.44 (0.36–0.62) |
Intakes of | |||||
Fructose, g/d | 24.2 (14.9–39.2) | 15.3 (10.0–24.4) | 20.0 (12.7–28.6) | 28.2 (19.0–39.7) | 43.0 (28.2–65.5) |
Vitamin C, mg/d | 120 (78–191) | 216 (116–606) | 123 (82–176) | 116 (80–163) | 84 (58–123) |
Energy, kcal/d | 2235 ± 911 | 2056 ± 891 | 2152 ± 875 | 2339 ± 913 | 2393 ± 923 |
Alcohol, g/d | 3.8 ± 11.9 | 3.5 ± 10.9 | 3.4 ± 9.5 | 4.3 ± 12.6 | 4.1 ± 14.0 |
Animal protein, g/d | 49.7 ± 28.9 | 47.1 ± 29.7 | 48.7 ± 28.2 | 51.7 ± 28.2 | 51.2 ± 29.2 |
SSBs, mL/d | 561 ± 792 | 232 ± 395 | 307 ± 450 | 572 ± 677 | 1130 ± 1096 |
Values are means ± SDs, medians (IQRs), or percentages. eGFR, estimated glomerular filtration rate; SSB, sugar-sweetened beverage.