Table 3.
Comparison of postintervention weight and laboratory test characteristics among hemodialysis patients randomized to the high-protein versus low-protein hemodialysis meal groups following study completion
| High-protein hemodialysis meal | Low-protein hemodialysis meal | P-value* | |
|---|---|---|---|
| Laboratory test characteristics Median (IQR) | |||
| Serum albumin (g/dL) | 3.8 (3.6–4.0) | 3.7 (3.5–3.9) | 0.151 |
| Phosphorus (mg/dL) | 5.2 (4.4–6.2) | 5.5 (4.5–6.6) | 0.433 |
| Calcium (mg/dL) | 8.8 (8.2–9.3) | 8.7 (8.1–9.0) | 0.331 |
| PTH (pg/mL) | 505 (239–703) | 330 (192–516) | 0.043 |
| Alkaline phosphatase (U/L) | 98 (73–119) | 77 (61–120) | 0.093 |
| nPCR (g/kg/day) | 1.00 (0.87–1.26) | 1.05 (0.79–1.34) | 0.556 |
| Bicarbonate (mEq/L) | 23 (21–25) | 23 (21–25) | 0.908 |
| Potassium (mEq/L) | 4.8 (4.5–5.2) | 4.9 (4.3–5.5) | 0.937 |
| Serum creatinine (mg/dL) | 9.2 (7.4–11.6) | 8.8 (6.5–11.3) | 0.520 |
| Blood urea nitrogen (mg/dL) | 59 (47–69) | 58 (48–74) | 0.676 |
| Serum prealbumin (mg/dL) | 24 (19–30) | 26 (22–34) | 0.293 |
| spKt/V | 1.69 (1.47–1.88) | 1.55 (1.40–1.86) | 0.214 |
| URR | 76 (72–79) | 74 (70–78) | 0.139 |
| Hemoglobin (g/dL) | 11.2 (10.4–11.9) | 11.3 (10.7–11.8) | 0.707 |
| WBC (×109/L) | 7.0 (5.7–8.7) | 7.4 (5.8–8.3) | 0.887 |
| Platelet count (×109/L) | 217 (175–268) | 222 (179–282) | 0.742 |
| LDL (mg/dL) | 63 (44–86) | 60 (42–79) | 0.671 |
| HDL (mg/dL) | 94 (65–177) | 93 (63–129) | 0.346 |
| Triglycerides (mg/dL) | 94 (65–177) | 93 (63–129) | 0.346 |
| TNF-α (pg/mL) | 5.45 (3.41–8.86) | 5.90 (3.55–10.67) | 0.910 |
| IL-6 (pg/mL) | 5.20 (3.41–9.85) | 6.09 (3.30–14.03) | 0.624 |
| Leptin (ng/mL) | 22.2 (7.2–81.3) | 24.5 (6.7–49.0) | 0.582 |
| C-reactive protein (mg/L) | 0.75 (0.35–1.60) | 0.48 (0.21–1.27) | 0.198 |
| Case-mix characteristics Median (IQR) | |||
| Weight (kg) | 73.4 (64.1–88.0) | 75.2 (64.8–92.3) | 0.602 |
| BMI (kg/m2) | 28.3 (24.2–31.9) | 27.5 (24.5–30.8) | 0.450 |
PTH, parathyroid hormone; nPCR, normalized protein catabolic rate; spKt/V, single-pool Kt/V; URR, urea reduction ratio; WBC, white blood cell count; LDL, low-density lipoprotein cholesterol; HDL, high-density lipoprotein cholesterol; TNF-α, tumor necrosis factor-α; IL-6, interleukin-6; BMI, body mass index.
*P-value calculated by Wilcoxon rank sum tests.