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Efficacy of AIA-1 against PAO1 biofilms. (a) Effects of AIA-1 on PAO1 biofilm formation. Killing assay for biofilm cells using (b) 32 mg/L biapenem, (c) 32 mg/L tobramycin and (d) 2 mg/L levofloxacin. By assuming that survival before AIA-1 exposure was 100%, cfu values were converted to percentages. *P < 0.05; ***P < 0.001; NS, not significant (Student’s t-test). Error bars show SDs for four experiments.
