Table I.
Overall demographics, baseline IVF characteristics, ovarian stimulation parameters and perinatal outcomes of the study cohort (n = 4071).
| Demographics | |
| Age (years) | 36 (33–39) |
| Gravidity | 1.3 (± 0.8) |
| Parity | 0.7 (± 0.2) |
| BMI (kg/m2) | 22.3 (20.4–25.0) |
| Race | |
| White | 2834 (69.6%) |
| Non-white | 1237 (30.4%) |
| Infertility diagnosis | |
| Male factor | 1443 (35.4%) |
| Tubal factor | 179 (4.4%) |
| Others | 2449 (60.2%) |
| Baseline IVF characteristics | |
| Cycle Days-2/3 FSH level (mIU/ml) | 4.12 (± 2.6) |
| Cycle Days-2/3 AMH level (ng/ml) | 1.8 (± 0.6) |
| Antral follicle count | 12.9 (± 2.1) |
| Ovarian stimulation parameters | |
| Ovarian stimulation protocol | |
| GnRH-agonist based | 1106 (27.2%) |
| GnRH-antagonist based | 2965 (72.8%) |
| Duration of ovarian stimulation (days) | 9.9 (± 2.6) |
| Dosage of gonadotropins (IU) | 2350.9 (± 437.1) |
| E2 level on the day of hCG trigger (pg/ml) | 1554 (1112.7–2179) |
| Peak endometrial thickness (mm) | 10.5 (8.80–12.1) |
| Total oocytes retrieved | 11.8 (± 2.9) |
| Mature oocytes retrieved | 10.3 (± 2.0) |
| Fertilization rate (%) | 79.4% |
| Blastocyst-stage ET (%) | 626 (15.4%) |
| Perinatal outcomes | |
| Mode of delivery | |
| Vaginal | 2319 (57.0%) |
| Cesarean | 1752 (43.0%) |
| Gender | |
| Male | 2102 (51.6%) |
| Female | 1969 (48.4%) |
| Birth weight (grams) | 3289 (2920–3628) |
| GA (weeks) | 38 (33–41) |
| Term birth (>37 weeks of gestation) | 3693 (90.7%) |
| PTB (<37 weeks of gestation) | 378/4071 (9.3%) |
| Overall LBW (<2500 g) | 209/4071 (5.1%) |
Data are presented as mean ± SD, median (IQR) and n (%).
LBW, low birth weight; IQR, interquartile range, AMH, anti-müllerian hormone; E2, estradiol; ET, embryo transfer; GA, gestational age; PTB, preterm birth.