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. Author manuscript; available in PMC: 2019 Oct 1.
Published in final edited form as: Contemp Clin Trials. 2018 Aug 20;73:111–122. doi: 10.1016/j.cct.2018.08.004

Figure 2.

Figure 2.

Bayesian response-adaptive design: Schematics of two possible scenarios of response-adaptive randomizations to dose groups.

Panel A: Scenario 1. A best dose is found during Stage 1 and that dose is compared to the control dose in Stage 2.

Panel B: Scenario 2. Stage 1 dose-finding continues to the end of the trial with no best dose identified.