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. Author manuscript; available in PMC: 2019 May 4.
Published in final edited form as: Chembiochem. 2018 Apr 6;19(9):963–969. doi: 10.1002/cbic.201700686

Figure 4:

Figure 4:

PrOF NMR data from synthesized analogs. A) Comparison of Y631 chemical shift perturbations in the presence of 1666 μM 1, 5 mM 1-OMe, and 1500 μM 2, 3, and 4. B) Y631 Binding isotherm for 2 demonstrating a slightly improved binding affinity for 3FY KIX.