Voxel-based analysis illustrating AMPH-induced BOLD activity in saline-pretreated (AMPH-naïve) (A) and AMPHpretreated, (B) adult (P90) rats maintained on the control diet (CON), fish oil-fortified diet (FO), and n-3-free diet (DEF) during periadolescent, development (P21–P90). (C) Contrasts illustrating differential AMPH-induced BOLD activity in AMPH-pretreated versus saline-pretreated rats maintained on CON, FO, or DEF diets. All contrasts used cluster significance threshold of P ≤ 0.05 (corrected). Bregma coordinates of each 1 mmslice are indicated. Abbreviations: ICj, islands of Calleja; Cg, cingulate cortex; M1, motor cortex; CPu, caudate putamen; NAc, nucleus accumbens; VP, ventral pallidum; Amy, amydgala; LH, lateral hypothalamus;Thal, thalamus; S1, somatosensory cortex; Sub, subiculum; SNR, substantia nigra.