Skip to main content
. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: ASAIO J. 2019 May-Jun;65(4):401–407. doi: 10.1097/MAT.0000000000000822

Figure 1.

Figure 1

Schematic representations of the extracorporeal circuits. Group 1: Standard right atrial to aortic CPB was performed using a clinical circuit. Group 2: The L-MOD was incorporated into the CPB circuit by creation of a parallel blood flow path post oxygenator. Regional citrate administration, which is essential to the therapeutic action, was performed and modulated blood was delivered into the arterial limb of the CPB circuit prior to blood returning to the animal. Group 3: L-MOD therapy was administered via regional citrate anticoagulation of an independent extracorporeal circuit with femoral venous access which allowed for continuation of therapy during the post-operative period.