Proliferation of Xenograft Tumors
Representative images of xenograft tumors extracted from mice, implanted with either wild-type A549 or NRF2-knockout A549 cells (2-11), 16 days after the initial treatment with either 2 mg/kg cisplatin or saline, were sectioned and stained with Ki67 (green) and DAPI (blue). Fluorescence intensity mean values for DAPI and Ki67 were obtained for the images using the Zeiss Zen software, and relative values were obtained for fluorescence intensity of Ki67. Scale bars represent 100 μm.