Table 3.

Levels of 5-FU of each sample (urine, serum, saliva) during 5-FU treatment and after completion of administration

Subject number	Samples	Before	After start of 5-FU administration							After finish of 5-FU administration
			30 min	90 min	3 h	12 h	36 h	60 h	120 h	30 min	60 min	3 h	12 h	36 h	48 h	72 h
1	Urine (mg/ml)	0		0.0011			0.0059	0.0100	0.0074				0	0	–	–
	Serum (μg/ml)	0		0.0270				0.2300	0.2600		0.0050	0.0060	0.0050	0	–	–
	Saliva (μg/ml)	0		0.0160				0.0100	0.0300	0.0050	0	0	0.0050	0	–	–
2	Urine (mg/ml)	0	0.0030			0.0120			0.0160		0.0190	0	0	0	–	–
	Serum (μg/ml)	0	0.0080		0.0260	0.0360			0.1200		0.0090	0	0	0	–	–
	Saliva (μg/ml)	0	0.0050	0.0050	0.0080	0.0160			0.0130	0.0480	0.0060	0	0	0	–	–
3	Urine (mg/ml)	0		0.0005	0.0013	0.0021	0.0200	0.0210	0.0230			0.0005	0	0	–	–
	Serum (μg/ml)	0		0.0070	0.0130	0.0180		0.0220	0.0180		0	0	0	0	–	–
	Saliva (μg/ml)	0	0	0	0.0050	0	0.0050	0	0	0	0	0	0	0	–	–
4	Serum (μg/ml)	0	17.2400	–	–	–	–	–	–	0	0	0	0	0	0	0
	Saliva (μg/ml)	0	8.0340	–	–	–	–	–	–	0.0700	0.0300	0.0150	0.0050	0.0050	0.0050	0