Fig. 1.

White blood cell (WBC) count, neutrophil (N) count, and platelet (PTL)  count were all within their normal ranges when the patient was first admitted. Proton pump inhibitor (PPI) therapy was adopted after he was hospitalized, and the levels of white blood cells and neutrophils decreased slowly afterward. The specific times when pantoprazole sodium and esomeprazole were used was as follows: pantoprazole sodium: 02/07/2017–16/07/2017, 10/08/2017–07/09/2017, 20/09/2017–22/09/2017, and 03/12/2017–07/12/2017; esomeprazole: 17/07/2017–09/08/2017, 08/09/2017–19/09/2017, and 23/09/2017–02/12/2017. Thrombocytopenia was found on December 5, 2017, while neutropenia appeared on December 7, 2017. PPI treatment was stopped on December 7, 2017, and the levels of these blood cells increased to normal slowly afterward