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. 2018 Jun 6;8(6):833–843. doi: 10.1016/j.apsb.2018.06.001

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© 2018 Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences. Production and hosting by Elsevier B.V.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 4 — Structure of m⁶A modification demethylase complexed with inhibitors. (A) Interaction between ALKBH5 and citrate. (B) Interaction between FTO and citrate. (C) Interaction between FTO and rhein. (D) Interaction between FTO and MA. (E) Interaction between FTO and compound 8. (F) Interactions between FTO and compound 9.