Fig. 5.

Naringin treatment causes cell cycle arrest at G1 phase of cells. (A) DU145 and (B) PC3 cells. The cells were treated with 150 μM naringin, 5 nM paclitaxel, 5 nM vincristine or their combination for 72 h. Cell cycle distribution was examined using a Tali cell cycle kit. *P < 0.05 between the untreated, ¢P < 0.01 versus paclitaxel or vincristine and naringin, ǂP<0.01 versus paclitaxel. **P < 0.05 between vincristine, paclitaxel, naringin, . Pac + Nar: combination of paclitaxel and naringin, Vin + Nar: combination of vincristine and naringin.