Table 3.
Comparison of the frequency of use of different inclusion and exclusion criteria across self-guided internet-based cognitive behavioral therapy (iCBT), face-to-face psychotherapy (F2F), and antidepressant medication (AM) trials.
| Exclusion criteria | iCBT (n=21) | F2F (n=16) | AM (n=170) | P value | ||
| iCBT vs F2F vs AM | iCBT vs F2F | iCBT vs AM | ||||
| Minimum symptom severity | 15 (71) | 13 (81) | 170 (100.0) | <.001 | .70 | <.001 |
| Maximum symptom severity | 6 (29) | 6 (38) | 14 (8.2) | <.001 | .83 | .01 |
| Psychosis | 12 (57) | 14 (88) | 143 (84.1) | .02 | .07 | .01 |
| Substance abuse or dependence | 5 (24) | 12 (75) | 137 (80.6) | <.001 | <.001 | <.001 |
| Suicidal risk | 13 (62) | 9 (56) | 128 (75.3) | .14 | .99 | .29 |
| Prior suicide attempt(s) | 1 (5) | 2 (12) | 35 (20.6) | .21 | .57 | .13 |
| Episode length too long | 1 (5) | 2 (12) | 34 (20.0) | .21 | .57 | .13 |
| Episode length too short | 1 (5) | 2 (12) | 81 (47.6) | <.001 | .57 | <.001 |
| Any axis II disorder | 0 (0) | 3 (19) | 60 (35.3) | <.001 | .07 | <.001 |
| Any axis I disorder | 1 (5) | 1 (6) | 46 (27.1) | .01 | >.99 | .03 |
| Borderline personality disorder | 0 (0) | 5 (31) | 70 (41.2) | <.001 | .01 | <.001 |
| Antisocial personality disorder | 0 (0) | 5 (31) | 68 (40.0) | <.001 | .01 | <.001 |
| Schizotypal personality disorder | 0 (0) | 5 (31) | 63 (37.1) | <.001 | .01 | <.001 |