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. Author manuscript; available in PMC: 2018 Nov 24.
Published in final edited form as: Optom Vis Sci. 2018 Apr;95(4):299–308. doi: 10.1097/OPX.0000000000001193

FIGURE 5.

FIGURE 5.

Optical coherence elastography measurements of central corneal thickness (CCT) and relaxation rates measured ex vivo in rabbit eyes (n = 6) before and after UV riboflavin cross-linking (CXL) treatment using isotonic riboflavin solution. Each color denotes the measurement from the same eye before and after treatment (paired analysis). Isotonic riboflavin (0.1% riboflavin dissolved in 2.5% dextran dissolved in 0.9% saline) did not affect CCT (−1%; mean difference, −5 μm; 95% confidence interval [CI], −21 to +32 μm; P = .62) but showed significantly greater relaxation rates (+10%; +0.24 ms−1; 95% CI, +0.08 to +0.4 ms−1; P = .01) after cross-linking treatment, indicating stiffer tissue biomechanical properties posttreatment.