Table 1.
Clinical characteristics of the total group of ACS patients and depending on the severity of signs and symptoms.
| ACS | STEMI | NSTEMI | UA | P-value | |
|---|---|---|---|---|---|
| N = 93 | N = 33 | N = 30 | N = 30 | STEMI vs. NSTEMI vs. UA | |
| Age (years) | 63 (29–93) | 62 (35–87) | 62 (29–85) | 66 (48–93) | |
| Sex: F/M | 34/59 | 13/20 | 11/19 | 11/19 | |
| Systolic BP [mmHg] | 140 (120–160) | 130 (116–160) | 150 (130–170) | 130 (120–160) | NS |
| Diastolic BP [mmHg] | 80 (70–90) | 80 (70–90) | 87 (80–96) | 80 (75–85) | NS |
| TCH [mg/dL] | 183 (159–211) | 179 (162–205) | 194 (157–224) | 183 (156–212) | NS |
| LDL [mg/dL] | 113 (80–135) | 108 (89–134) | 120 (83–139) | 99 (73–131) | NS |
| HDL [mg/dL] | 49 (41–59) | 50 (42–57) | 43 (38–56) | 49 (43–61) | NS |
| TG [mg/dL] | 105 (68–148) | 99 (57–131) | 106 (76–148) | 111 (71–198) | NS |
| Glucose [mg/dL] | 102 (93–112) | 104 (94–129) | 105 (101–126) | 93 (86–101) | 0.0012⁎ |
| Sodium [mmol/L] | 139 (137–140) | 138 (135–140) | 139 (136–140) | 140 (139–141) | 0.0034⁎ |
| Potassium [mmol/L] | 4.26 (3.96–4.50) | 4.25 (3.88–4.42) | 4.25 (3.96–4.47) | 4.28 (4.13–4.50) | NS |
| Creatinine [mg/dL] | 0.88 (0.71–0.99) | 0.88 (0.71–1.01) | 0.82 (0.71–0.95) | 0.88 (0.78–0.97) | NS |
| eGFR [mL/min/1.73m2] | 91 (76–104) | 92 (77–108) | 93 (81–104) | 88 (70–101) | NS |
| Urea [mg/dL] | 38 (31–43) | 40 (33–43) | 33 (26–40) | 39 (31–47) | NS |
| AST [U/I] | 29 (20–79) | 53 (28–116) | 44 (19–79) | 20 (16–22) | 0.0013⁎ |
| ALT [U/I] | 22 (15–35) | 27 (20–37) | 25 (14–41) | 20 (13–26) | NS |
| RBC [x106/μL] | 4.61 (4.26–4.95) | 4.53 (4.10–5.11) | 4.69 (4.46–5.93) | 4.56 (4.32–4.95) | NS |
| HGB [g/dL] | 14.2 (13.2–15.0) | 14.0 (12.0–14.9) | 14.2 (13.5–15.3) | 14.3 (13.1–15.4) | NS |
| HCT [%] | 41.4 (38.1–43.7) | 40.8 (36.2–43.8) | 41.0 (39.3–43.5) | 42.2 (38.0–44.2) | NS |
| Troponin I [ng/mL] | 9.28 (0.22–25.00) | 25.00 (25.00–25.00) | 9.28 (6.06–23.4) | 0.10 (0.10–0.14) | 0.0000⁎ |
| 1-vessel disease [N] | 40 (43%) | 17 (43%) | 11 (27%) | 12 (30%) | |
| 2-vessels disease [N] | 24 (26%) | 10 (42%) | 9 (37.5%) | 5 (20.5%) | |
| 3-vessels disease [N] | 19 (21%) | 5 (26%) | 8 (42%) | 6 (32%) |
ACS – acute coronary syndrome, F – female, M – male, BP – blood pressure, TCH – total cholesterol, LDL – low-density lipoprotein cholesterol, HDL – high-density lipoprotein cholesterol, TG – triglycerides, eGFR – estimate glomerular filtration rate, AST – aspartate transaminase, ALT – alanine transaminase, RBC – red blood cell count, HGB - hemoglobin, HCT – hematocrit, STEMI – ST-segment elevation myocardial infarction, NSTEMI – non-ST-segment elevation myocardial infarction, UA – unstable angina, NS – not statistically significant.
Conversion factors to SI units are as follows: for glucose – 0.0555, for TCH – 0.0259, for LDL – 0.0259, for HDL – 0.0259, for TG - 0.0113, for creatinine – 88.4, for urea – 59.48, for RBC – 1.0, for HGB – 10.0, for HCT – 0.01.
The analysis of differences between the ACS subgroups showed that significant variations were found, therefore in the next step the post hoc Dwass-Steele-Critchlow-Fligner test was conducted. Obtained P-value results are as follows: Glucose: STEMI vs. NSTEMI = NS, STEMI vs. UA = 0.0321, NSTEMI vs. UA = 0.0011; Sodium: STEMI vs. NSTEMI = NS, STEMI vs. UA = 0.0030, NSTEMI vs.UA = NS; AST: STEMI vs. NSTEMI = NS, STEMI vs. UA = 0.0008, NSTEMI vs. UA = NS.