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. Author manuscript; available in PMC: 2019 Dec 1.
Published in final edited form as: J Vasc Surg. 2018 Jun 15;68(6 Suppl):165S–176S.e6. doi: 10.1016/j.jvs.2018.03.436

Figure 6.

Figure 6

Effects of opposing cell types on growth, according to smoking status (panel A - left) and p27 SNP genotype (panel B - right). Current smoking decreases the inhibitory influence of adventitial cells on SMC growth, but not the stimulatory effect of SMCs on adventitial cells. N= 19 pairs of cells total, 13 for current smoking. *P<.01 smoking vs. no smoking. The protective AA p27 SNP genotype leads to more stimulation of adventitial cell growth by SMCs and a trend for more inhibition of SMC growth by adventitial cells. N=19 pairs of cells total, 10 for for AA. *P<.04, AA vs. CC.