Perivascular delivery of resolvin D1 (RvD1) inhibits proliferation within vein grafts 3 days after bypass. Vein grafts were harvested at 3 days after bypass and stained for Ki67 to detect proliferation (green). 4ā,6-Diamidino-2-phenylindole (DAPI) counterstaining was also performed (blue). The Ki67 index was calculated by the number of Ki67-positive cells in the vessel wall divided by the total number of nucleated (DAPI-positive) cells. A-E, Representative images. F, Quantitative analysis was performed using three sections from each graft. ANOVA, Analysis of variance; L, lumen; Veh, vehicle.