Table 3.
ApolipoproteinL1 (APOL1)Genetic Testing Pros and Cons
| Responses | Mean +/− SD^ | |||||
|---|---|---|---|---|---|---|
| Strongly Disagree | Disagree | Agree | Strongly Agree | |||
| 3. | My genetic test results could help me make better decisions about how to take care of my health.* | 1 (4) | 1 (4) | 8 (35) | 12 (52) | 3.41 [0.8] |
| 5. | Knowing that I carry 2 APOL1 gene variants would motivate me to better watch my health.* | 1 (4) | 1 (4) | 8 (35) | 12 (52) | 3.41 [0.8] |
| 4. | Genetic testing would help me learn if I were at greater risk for getting kidney disease after donating.* | 1 (4) | 0 | 10 (44) | 11 (48) | 3.41 [0.7] |
| 6. | Knowing that I carry 2 APOL1 gene variants would help me decide whether to go for more frequent kidney checks.* | 1 (4) | 0 | 12 (52) | 9 (39) | 3.32 [0.7] |
| 2. | My genetic test results could give me useful information about the risk of getting kidney disease after donating.* | 2 (9) | 0 | 9 (39) | 11 (48) | 3.32 [0.9] |
| 7. | My concerns about getting kidney disease after donating would be reduced if I knew I did not carry APOL1 gene variants.** | 1 (4) | 1 (4) | 11 (48) | 8 (35) | 3.24 [0.8] |
| 9. | Knowing whether I have 2 APOL1 gene variants would help me decide whether to donate.** | 2 (9) | 2 (9) | 9 (39) | 8 (35) | 3.10 [0.9] |
| 11. | If I donated, after learning that I have 2 APOL1 gene variants I would worry about the recipient’s kidney transplant survival.* | 0 | 3 (13) | 16 (70) | 3 (13) | 3.00 [0.5] |
| 8. | Knowing whether I had 2 APOL1 gene variants would increase my sense of personal control over my health.* | 2 (9) | 4 (17) | 9 (39) | 7 (30) | 2.95 [1.0] |
| 13. | If I did not donate because I had 2 APOL1 gene variants, I would feel guilty about my recipient not getting a living donor kidney transplant.* | 2 (9) | 4 (17) | 11 (48) | 5 (22) | 2.86 [0.9] |
| 1. | If I were found to carry the 2 APOL1 gene variants, it would help my intended transplant recipient decide whether to accept a kidney from me.** | 1 (4) | 5 (22) | 12 (52) | 3 (13) | 2.81 [0.8] |
| 12. | If I learned, after donating, that I had 2 APOL1 gene variants, I would feel guilty if my recipient’s kidney rejected.* | 1 (4) | 7 (30) | 10 (44) | 4 (17) | 2.77 [0.8] |
| 10. | If I learned that I had 2 APOL1 gene variants, I would consider not donating.* | 1 (4) | 10 (44) | 9 (39) | 2 (9) | 2.55 [0.7] |
| 14. | If I underwent genetic testing and learned that I had 2 APOL1 gene variants, this information would be emotionally burdensome.* | 1 (4) | 10 (44) | 9 (39) | 2 (9) | 2.55 [0.7] |
| 16. | Being tested for APOL1 gene variants could jeopardize my insurance coverage.* | 3 (13) | 11 (48) | 4 (17) | 4 (17) | 2.41 [1.0] |
| 15. | If I were found to carry APOL1 gene variants, I would worry that the results would not stay confidential.* | 4 (17) | 16 (70) | 0 | 2 (9) | 2.00 [0.8] |
*
One participant skipped this question. Percentages are based on n=22.
**
Two participants skipped this question. Percentages are based on n=21.
^
SD = Standard Deviation.