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. Author manuscript; available in PMC: 2019 Jun 8.
Published in final edited form as: ACS Infect Dis. 2018 Mar 26;4(6):1019–1029. doi: 10.1021/acsinfecdis.8b00037

Figure 4. Ability of PcephPT to kill MG1655 bacteria depends on both the presence of β-lactamase and availability of Cu.

Figure 4.

Bacteria treated with minimal growth-inhibiting concentrations of PcephPT or PT with and without supplemental CuCl2 (10 μM) in liquid medium for 20 h were plated on fresh agar and incubated at 37 °C for 24 h prior to enumeration of colonies. Each point on the graph is an individual replicate. 0 h CFU/mL values: null = 5900, TEM-1 = 38000, CTX-M-1 = 35000, CMY-2 = 19000, NDM-1 = 47000. CFUs above 12500 were not enumerated and are grouped collectively on the plot as >12500.