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Substrate scope and expected hydrolysis of PcephPT by the β-lactamases expressed in MG1655 and UTI89 E. coli background strains.
| Name | Ambler Class | Active Site | Substrates | Expected to cleave PcephPT? |
|---|---|---|---|---|
| null | – | – | No | |
| OXA-1 | D | Ser | Penicillins | No |
| TEM-1 | A | Ser | Penicillins, some cephalosporins | Yes |
| CTX-M-1 | A | Ser | Penicillins, cephalosporins | Yes |
| CMY-2 | C | Ser | Penicillins, cephalosporins | Yes |
| NDM-1 | B | Zn | Penicillins, cephalosporins, carbapenems | Yes |
