Fig. 6.

Bach1 deficiency ameliorated DSS-induced colitis. (A) The histological appearance of colonic tissue in wild type mice and Bach1-deficient mice without or with DSS induced-colitis. Hematoxylin and eosin staining. Magnification, ×40. (B) Histological score was evaluated as described in Materials and Methods. Data represent the mean ± SE of 5 mice. *p<0.05 compared to wild type mice with DSS induced-colitis. (C) Tissue-associated neutrophil accumulation in the colonic mucosa expressed as myeloperoxidase (MPO) activity. Each value indicates the mean ± SE for 7 mice. *p<0.05 compared with wild type mice without 2% DSS solution, ^#p<0.05 compared with wild type mice receiving 2% DSS solution.