Table 2.
Cytotoxicity of 111In-NOTA-DTox-HMP-NLS-EGF and free 111In on cancer cell lines.
| Cell line | A37, MBq/ml |
Enhancement of cytotoxicity, times | |
|---|---|---|---|
| 111In-NOTA-MNT | 111In | ||
| A431 | 0.023 | 6.3 | 271 |
| HT1376 | 0.19 | 13.0 | 70 |
| EJ | 0.039 | 2.22 | 57 |
| 5637 | 0.41 | 10.5 | 19 |
A37, value of radioactivity that reduces cell survival by a factor of “e.”