Table 3.

¹¹¹In radioactivity in mouse tissues after intratumoral injection of ¹¹¹In-NOTA-DTox-HMP-NLS-EGF into EJ human bladder cancer xenografts (percent ID per gram of tissue, mean ± standard deviation).

Time Tissue	5 min	1 h	3 h	1 day	2 days	5 days
Blood	0.244 ± 0.046	0.318 ± 0.076	0.167 ± 0.010	0.062 ± 0.017	0.025 ± 0.001	0.017 ± 0.006
Tumor	367 ± 101	370 ± 176	463 ± 123	566 ± 77	264 ± 79	80 ± 63
PT skin	5.9 ± 7.8	46.9 ± 12.4	50.4 ± 24.7	58.0 ± 23.9	61.7 ± 4.0	49.0 ± 19.0
RLN	40.5 ± 38.6	45.9 ± 57.1	73.6 ± 1.5	71.0 ± 7.3	67.0 ± 34.6	41.5 ± 22.4
Liver	0.70 ± 0.60	1.18 ± 0.27	1.40 ± 0.55	1.65 ± 0.52	1.54 ± 0.40	1.33 ± 0.23
Kidney	1.82 ± 0.97	13.3 ± 5.17	12.0 ± 1.12	12.1 ± 2.8	7.71 ± 1.99	3.07 ± 2.37
Lung	0.30 ± 0.14	0.23 ± 0.10	0.135 ± 0.017	0.094 ± 0.004	0.063 ± 0.031	0.037 ± 0.016
Spleen	0.25 ± 0.18	0.280 ± 0.092	0.43 ± 0.11	0.62 ± 0.28	0.57 ± 0.22	0.52 ± 0.13
Bones	0.198 ± 0.028	1.19 ± 0.36	0.44 ± 0.18	0.578 ± 0.071	0.55 ± 0.47	0.43 ± 0.31
Bladder	0.260 ± 0.13	0.196 ± 0.073	0.253 ± 0.083	0.074 ± 0.013	0.051 ± 0.038	0.041 ± 0.021
Stomach	0.29 ± 0.10	0.35 ± 0.23	0.213 ± 0.008	0.140 ± 0.076	0.080 ± 0.031	0.075 ± 0.052
Intestine	0.134 ± 0.041	0.203 ± 0.098	0.255 ± 0.092	0.125 ± 0.017	0.093 ± 0.012	0.053 ± 0.043
Heart	0.21 ± 0.13	0.155 ± 0.076	0.083 ± 0.006	0.090 ± 0.026	0.059 ± 0.008	0.023 ± 0.012
Muscles	0.32 ± 0.29	0.34 ± 0.23	0.246 ± 0.078	0.206 ± 0.064	0.20 ± 0.15	0.168 ± 0.045
Skin	0.079 ± 0.019	0.610 ± 0.057	0.180 ± 0.071	0.325 ± 0.049	0.205 ± 0.021	0.225 ± 0.064

PT, peritumoral skin samples; RLN, regional lymph node.