Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Sep 10;55(11):729–734. doi: 10.1136/jmedgenet-2018-105427

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Author(s) (or their employer(s)) 2018. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

PMC Copyright notice

Estimated lifetime penetrance of pheochromocytoma/paraganglioma (PC/PGL) in subjects heterozygous for genetic variants in succinate dehydrogenase subunits A, B and C (SDHA, SDHB and SDHC) from cohorts 1 and 2 combined. The algorithm used to calculate these estimates is based on Minikel et al ²² and takes into account allelic frequencies in cases versus Exome Aggregate Consortium (ExAC) controls and estimated population prevalence of these disorders.