Table 2.
MIC and MBC/MFC values for crude extracts of plant parts against Multi-Drug Resistant strains of Nosocomial and Community Acquired Infections and susceptible standard strains
Microorganism | MIC(µg/mL) and MBC/MFC (µg/mL) of crude herbal extracts | ||||||||||||||||||
A. nilotica* | T. arjuna | E. globulus | S. aromaticum | C. zeylanicum | |||||||||||||||
MIC | MBC/MFC | MIC | MBC/MFC | MIC | MBC/MFC | MIC | MBC/MFC | MIC | MBC/MFC | ||||||||||
S. mutans | 78 | 313 | 1560 | 3130 | 3130 | 6250 | 390 | 780 | 195 | 390 | |||||||||
S. aureus | 39 | 78 | 780 | 1560 | 6250 | 12500 | 780 | 1560 | 390 | 1560 | |||||||||
E. faecalis | 9.75 | 78 | 1560 | 3130 | 3130 | 12500 | 195 | 1560 | 97.5 | 1560 | |||||||||
S. bovis | 39 | 78 | 1560 | 3130 | 3130 | 12500 | 780 | 1560 | 195 | 390 | |||||||||
P. aeruginosa | 39 | 39 | - | - | - | - | 390 | 1560 | 390 | 1560 | |||||||||
S. typhimurium | 9.75 | 39 | - | - | - | - | 1560 | 1560 | 1560 | 3130 | |||||||||
E. coli | 19.5 | 39 | - | - | - | - | 780 | 1560 | 390 | 1560 | |||||||||
C. albicans | 4.9 | 19.5 | - | - | - | - | 156 | 156 | 19.5 | 78 | |||||||||
K. pneumoniae | 9.75 | 78 | - | - | - | - | 390 | 6250 | 195 | 3130 | |||||||||
E. coli [10] a) | 156 | 313 (3/10) | - | - | - | - | 6250 | 12500 (10/10) | 3130 | 6250 (7/10) 12500 (3/10) |
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E. coli [16] b) | 19.5 | 39 (3/16) | - | - | - | - | 390 | 1560 (2/16) 3130 (14/16) |
195 | 1560 (11/16) 3130 (5/16) |
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C. albicans [18]c) | 9.5 | 39 (9/18) | - | - | - | - | 390 | 780 (3/18) 3130 (15/18) |
780 | 1560 (18/18) |
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K. pneumoniae [14]d) | 156 | 313 (11/14) | - | - | - | - | 780 | 1560 (4/14) | 390 | 1560 (11/14) |
MIC = minimum inhibitory concentration; MBC = minimum bactericidal concentration; MFC = minimum fungicidal concentration; a) & c) = isolates of nosocomial infection; b) & d) = isolates of community acquired infection; * value in parentheses indicates number of isolates out of total isolates tested.; – = No activity at the concentration of the extracts tested.