Scheme 1a.
a Reagents and conditions: (a) EDCI, Et3N, CH2Cl2, 25 °C; (b) saturated HCl in methanol, 25 °C; (c) (i) benzaldehyde, MgSO4, K2CO3, CH2Cl2, 25 °C, (ii) NaBH4, 0 °C; (d) pyridine, 25 °C; R2 is as indicated in Table 1.
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