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Involvement of miR-205-5p in cisplatin resistance via PTEN/AKT pathway in ovarian cancer cells. Relative expression of PTEN mRNA (A) and protein (B) in C13K and OV2008 cells (∗P < 0.01). (C,D) Inhibition of miR-205-5p increased PTEN and decreased p-AKT in C13K cells with cisplatin treatment for 48 h. (E,F) Overexpression of miR-205-5p decreased PTEN and increased p-AKT in OV2008 with cisplatin treatment for 48 h.
