Table 3.

Hazard ratio and 95% confidence interval of cancer associated with weight loss and comorbidities

Variable	Crude	Adjusted†
	HR (95% CI)	HR	(95% CI)
Sex (male vs. female)	1.66(1.52, 1.82)	2.06	(1.87, 2.26)
Age (per one year)	1.05(1.04, 1.05)	1.51	(1.38, 1.66)
Weight loss (yes vs. no)	1.99(1.81, 2.19)	1.05	(1.04, 1.05)
Baseline comorbidities (yes vs. no)
Alcohol-related disease	1.86(1.56, 2.23)	1.81	(1.50, 2.18)
Chronic obstructive pulmonary disease	1.96(1.79, 2.16)	0.98	(0.89, 1.08)
Chronic liver disease	1.55(1.42, 1.70)	1.34	(1.22, 1.47)
Diabetes mellitus	2.59(2.31, 2.90)	1.63	(1.45, 1.83)

^†Variables found to be statistically significant in the univariable model were further examined in the multivariable model. Adjusted for sex, age, alcohol-related disease, chronic obstructive pulmonary disease, chronic liver disease, and diabetes mellitus.