Table 1.
Changes in A549 cell PC species after 2OHOA treatment
After treatment with 2OHOA (200 μm), cells were homogenized, and protein concentrations were measured. Cell homogenates with the same protein concentration were used for lipid extraction. PC peak areas were obtained after LC/MS/MS analysis. Values (arbitrary units) are mean ± S.D., n = 3. NS, not significant.
PC | Control | 2OHOA | p value |
---|---|---|---|
16:0/16:0 | 15.31 ± 1.18 | 15.87 ± 0.98 | NS |
16:0/18:1 | 66.29 ± 4.58 | 53.84 ± 4.07 | <0.02 |
18:0/20:4 | 1.41 ± 0.02 | 0.89 ± 0.05 | <0.001 |
18:1/16:0 | 47.14 ± 4.14 | 39.07 ± 3.09 | <0.05 |
18:1/18:0 | 4.93 ± 0.38 | 4.20 ± 0.22 | <0.05 |